![]() The prevalence of SLE in Africa and Asia is believed to be much lower than in Western nations however, in industrialized Western countries, people of African and Asian descent are two to four times more likely to develop SLE than are people of European descent. It is most common in younger women, peaking during the childbearing years however, 20 percent of SLE cases occur in people over age 50.įor unknown reasons, in industrialized Western countries SLE has become 10 times more common over the past 50 years. ![]() Females develop SLE about nine times more often than males. Diagnosis may be delayed for years, and the condition may never be diagnosed in some affected individuals. The exact prevalence is difficult to determine because many of the signs and symptoms of SLE resemble those of other disorders. SLE has been estimated to affect between 322,000 and 1.5 million people in the United States. Overall, SLE gradually gets worse over time, and damage to the major organs of the body can be life-threatening. People with SLE have episodes in which the condition gets worse (exacerbations) and other times when it gets better (remissions). Anxiety and depression are also common in SLE. The inflammation characteristic of SLE can also damage the nervous system, and may result in abnormal sensation and weakness in the limbs (peripheral neuropathy) seizures stroke and difficulty processing, learning, and remembering information (cognitive impairment). Heart disease caused by fatty buildup in the blood vessels ( atherosclerosis ), which is very common in the general population, is even more common in people with SLE. Heart problems may also occur in SLE, including inflammation of the sac-like membrane around the heart (pericarditis) and abnormalities of the heart valves, which control blood flow in the heart. Affected individuals may also have hair loss (alopecia) and open sores (ulcerations) in the moist lining (mucosae) of the mouth, nose, or, less commonly, the genitals.Ībout a third of people with SLE develop kidney disease (nephritis). Petechiae are caused by a shortage of cells involved in clotting (platelets), which leads to bleeding under the skin. Other skin problems that may occur in SLE include calcium deposits under the skin (calcinosis), damaged blood vessels (vasculitis) in the skin, and tiny red spots called petechiae. The rash, which generally does not hurt or itch, often appears or becomes more pronounced when exposed to sunlight. A characteristic feature is a flat red rash across the cheeks and bridge of the nose, called a "butterfly rash" because of its shape. Most affected individuals also have joint pain, typically affecting the same joints on both sides of the body, and muscle pain and weakness. SLE may first appear as extreme tiredness (fatigue), a vague feeling of discomfort or illness (malaise), fever, loss of appetite, and weight loss. SLE is one of a large group of conditions called autoimmune disorders that occur when the immune system attacks the body's own tissues and organs. ![]() The signs and symptoms of SLE vary among affected individuals, and can involve many organs and systems, including the skin, joints, kidneys, lungs, central nervous system, and blood-forming (hematopoietic) system. ![]() Connect the computer to the Internet and make sure the Internet connection remains active during the installation process.Systemic lupus erythematosus (SLE) is a chronic disease that causes inflammation in connective tissues, such as cartilage and the lining of blood vessels, which provide strength and flexibility to structures throughout the body. Verify that the computer is connected to the Internet.ĭuring the installation, the software will be activated online. The serial number is read from the upper-left to the lower-right.Ģ. The serial number is broken down into three lines, each line contains four numbers. The serial number is a 12-digit number, which is indicated on the bottom of the camcorder. Check the serial number of the camcorder. ImageMixer 3 SE Ver.6 Video Tools and ImageMixer 3 SE Player Ver.6 can be installed from Disc 2.ġ. To install the software on Disc 2, continue to the next section. If you want to change the destination folder, click and select a different folder.Ħ.Click to begin the installation.ħ.Once the installation is completed, click. īy default, the software is installed in the following location.Ĭ:\Program Files\PIXELA\ImageMixer 3 SE Ver.6\Transfer Utility You cannot install the software otherwise.ĥ.Check the destination folder for the installation files and click. Select in the window that opens.Ĭlick when the dialog box is displayed.Ģ.Select the language for the installation and click.
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